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Forensic Applications of High Performance Liquid Chromatography


Forensic Applications of High Performance Liquid Chromatography

Paperback by Bayne, Shirley (University of Teesside, Middlesbrough, UK); Carlin, Michelle (Northumbria University, UK)

Forensic Applications of High Performance Liquid Chromatography

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ISBN:
9781420091915
Publication Date:
15 Jan 2010
Language:
English
Publisher:
Taylor & Francis Inc
Imprint:
CRC Press Inc
Pages:
276 pages
Format:
Paperback
For delivery:
Estimated despatch 27 May - 1 Jun 2024
Forensic Applications of High Performance Liquid Chromatography

Description

Chromatography has many roles in forensic science, ranging from toxicology to environmental analysis. In particular, high-performance liquid chromatography (HPLC) is a primary method of analysis in many types of laboratories. Maintaining a balance between practical solutions and the theoretical considerations involved in HPLC analysis, Forensic Applications of High Performance Liquid Chromatography uses real-life examples likely to be found within a forensic science laboratory to explain HPLC from a forensic perspective. Focusing chiefly on the reverse phase HPLC mode of separation, this volume examines: The history of HPLC and the theory behind the separation process The requirements for successful analysis and best practice tips The modes of separation and detection most appropriate for forensic science applications HPLC method development and evaluation The quality aspects of laboratory operation Troubleshooting HPLC systems and analyses Applications of HPLC within the field of forensic science Designed as a textbook for university students studying analytical chemistry, applied chemistry, forensic chemistry, or other courses with an element of HPLC within the course curriculum, this volume is also an invaluable guide for those in the early stages of their forensic analysis careers. An instructor's manual with lecture slides, test bank, objectives, and exercises is available with qualifying course adoption

Contents

Introduction to HPLC. Basic Principles of HPLC. Mobile Phase Preparation, the Use of Buffers, and Sample Preparation. Modes of Separation. Detection Systems. Method Development in Reversed Phase HPLC. System Suitability. Qualification, Validation, and Verification. Quality Systems. Troubleshooting HPLC Systems. Forensic Applications of HPLC. Glossary. Index.

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