Microbial Forensics is a rapidly evolving scientific discipline. In the last decade, and particularly due to the anthrax letter attacks in the United States, microbial forensics has become more formalized and has played an increasingly greater role in crime investigations. This has brought renewed interest, development and application of new technologies, and new rules of forensic and policy engagement. It has many applications ranging from biodefense, criminal investigations, providing intelligence information, making society more secure, and helping protect precious resources, particularly human life. A combination of diverse areas is investigated, including the major disciplines of biology, microbiology, medicine, chemistry, physics, statistics, population genetics, and computer science.
Microbial Forensics, Second Edition is fully revised and updated and serves as a complete reference of the discipline. It describes the advances, as well as the challenges and opportunities ahead, and will be integral in applying science to help solve future biocrimes.
Introduction - The Rapidly Evolving Discipline of Microbial Forensics;
PART 1 INVESTIGATIVE GENETICS - A. Criminal; The Kameido anthrax incident: A microbial forensics case study; Microbial Forensic Investigation of the Anthrax-Letter Attacks;
B. Civilian; Foodborne Outbreaks: What's New, What's Not, and Where Do We Go from Here?; Genotype and Geography; the global distribution of bovine tuberculosis; Tracing meat products through production and distribution chain from farm to consumer; Microbial Forensics of RNA Viruses: Foot-and-Mouth Disease Virus; Forensic Plant Pathology;
PART 2 EMERGING INFECTIONS Influenza Forensics; Keeping Track of Viruses; Microbial Forensic Analysis of Trace and Unculturable Specimens; Molecular Microbial Surveillance and Discovery in Bioforensics;
PART 3 BIOSECURITY Assessment of the Threat; The Select Agent Regulations; Biosurety in the Post-9/11 Era; Forensic public health: epidemiologic & microbiologic investigations for biosecurity
PART 4 SUBJECT AREAS Forensic Analysis in Bacterial Pathogens; Rickettsia and Coxiella; Forensics and Epidemiology of Fungal Pathogens; Ricin Forensics: Comparisons to Microbial Forensics; Forensic Aspects of Biologic Toxins;
PART 5 METHODS The Use of Host Factors in Microbial Forensics; Collection and Preservation of Microbial Forensic Samples; Sampling for Microbial Forensic Investigations; Toxin Analysis Using Mass Spectrometry; Electron Beam-Based Methods for Bioforensic Investigations; Proteomics Development and Application for Bioforensics; High-throughput Sequencing; Genomics; The Design of Genomic Signatures for Pathogen Identification and Characterization; Non-Biological Measurements on Biological Agents; Inferential Validation and Evidence Interpretation; Microbial Forensic Investigations in the Context of Bacterial Population Genetics; Population Genetic Considerations in Statistical Interpretation of Microbial Forensic Data; Biorepositories and their Foundations - Microbial Forensic Considerations;
PART 6 NATIONAL LEVEL CAPABILITIES A U.S. Research Strategy for Microbial Forensics: From Genesis to Implementation; The National Bioforensic Analysis Center; Microbial Forensics in Australia - The Australian Federal Police Perspective; Validation of Microbial Forensics in the Scientific, Legal and Policy Contexts;
PART 7 MICROBIAL FORENSICS CURRICULA AND TRAINING Microbial Forensics: Educating the Workforce and the Community; So You Really Want to be an Expert Witness? A Primer for the Occasional Expert Witness; Conclusion - Microbial Forensics, What Next?
